Alicia made her film debut in David Lynch's Dune (1984) and, by the age of fourteen, received her high school diploma and moved to Los Angeles, California, to pursue acting full-time. Once in Los Angeles, Lynch cast her in his Emmy Award-winning cult classic television series "Twin Peaks" (1990) as Gersten Hayward, a part written specifically for her. Following this, Lynch utilized Alicia's talents once again in his HBO trilogy "Hotel Room" (1993), in which she portrayed a young woman with multiple personality disorder. Alicia appeared in Mr. Holland's Opus (1995), opposite Richard Dreyfuss; as well as Four Rooms (1995) (Miramax/Buena Vista) with Tim Roth, Madonna Ciccone, and Lili Taylor, which was directed by Quentin Tarantino, Alison Sanders, Robert Rodriguez, and Alexandre Rockwell. In 1994, Witt appeared in the critically acclaimed Fun (1994), which debuted at the Sundance Film Festival. The film, directed by Rafal Zielinski, depicts a tale of two disturbed young girls whose quest for fun leads them to murder. Witt received the Special Jury Recognition Award at Sundance and a nomination for an Independent Spirit Award. Other credits include Mike Figgis's Liebestraum (1991), starring Kevin Anderson; Bodies, Rest & Motion (1993), starring Tim Roth and Bridget Fonda; and Bongwater (1997) opposite Luke Wilson.She combined her acting talents with her skills as a classically trained pianist in the romantic comedy Playing Mona Lisa (2000). For this role, Alicia won a Best Actress Award at the US Comedy Arts Festival. Alicia has made guest appearances on the phenomenally successful HBO series "The Sopranos" (1999) and the Emmy award-winning "Ally McBeal" (1997) In 1998, Alicia starred in Columbia Tristar's hit movie Urban Legend (1998). CBS was Witt's home for four years where she starred as Zoey, Cybill Shepherd's quirky daughter with a dark side, on the sitcom "Cybill" (1995) (Carsey Warner).More recently, Witt was in The Upside of Anger (2005) opposite Kevin Costner & Joan Allen and is also in Ring of the Nibelungs (2004) (TV), which was shot in South Africa. She was last seen starring in the Warner Bros. romantic comedy Two Weeks Notice (2002) opposite Hugh Grant and Sandra Bullock. She was also seen in the John Waters film Cecil B. DeMented (2000), starring Stephen Dorff and Melanie Griffith. Alicia also made a cameo in the independent film American Girl (2002/I).